Two Blind Brothers co-founders Bryan and Bradford Manning discuss how ChatGPT helps them work and live more independently as people with low vision. They share how they use it to take on tasks that previously required help, including reviewing documents and building a website. They also discuss why voice features matter and what could make AI more accessible.

Professor César de la Fuente joined Chris Nicholson to discuss how his lab uses AI to discover potential antibiotics, including molecules found in ancient biology. He explained how ChatGPT supports brainstorming across disciplines and how Codex helps scientists who have never programmed write code. The conversation also covered how researchers choose promising candidates for lab testing and what faster discovery could make possible. For more on Professor de la Fuente, check out his social media: [X](https://x.com/delafuentelab), [LinkedIn](https://www.linkedin.com/in/cesardelafuentenunez/), and [Bluesky](https://bsky.app/profile/delafuentelab.bsky.social).

The GitLab Foundation, in partnership with OpenAI, held its second annual demo day to showcase 15 innovative grantee projects aimed at driving economic mobility. The event highlighted how artificial intelligence can be used to improve the lives of individuals by increasing lifetime earnings and reducing economic barriers. Project presenters, in order of appearance: Terrina Govender Heath, Director, Open Weather Initiative Shweta Bhogale, Lead Researcher, Development Innovation Lab Caitlyn Brazill, President, Per Scholas Lois Lupica, Lead Designer, Community Economic Defense Project Paul Gilson, Vice President of Strategic Initiatives, Community Economic Defense Project Ayush Chopra, Co-Founder, Iceberg Systems Cassandra Okechukwu, Chief Science Officer, National Association of Community Health Centers Harpreet Marwah, Product Lead, TruePath Navigator, Career Path Services Allison Johnson, Director, Open UI, National Association of State Workforce Agencies Kelly Smyth, Chief, Office of Workforce Data & Research, New York State Department of Labor Ai-jen Poo, President, National Domestic Workers Alliance Elza Monteiro, Home Care Council Member, National Domestic Workers Alliance Christine Heitz, CEO, Colorado Thrives Steve Lee, CEO, SkillUp Coalition Deborah Singer, Chief Marketing Officer, Moms First Mike Marriner, Co-Founder & President, Roadtrip Nation Myles Sutholt, Head of Product and Design, Field Intelligence Kavitta Ghai, Co-Founder & CEO, Nectir

In this OpenAI Forum conversation, Sébastien Bubeck joins mathematicians Jacob Tsimerman, Daniel Litt, and Po-Shen Loh to explore how AI could reshape mathematical research and education. Filmed on August 11, 2026, the discussion examines what makes a mathematical result valuable, from solving long-standing problems to generating new ideas and discoveries. The panel also considers how students can use AI as a learning tool and, looking ahead, how AI could help mathematicians tackle harder questions and rethink mathematics’ role in the wider world.

Richard Ho, OpenAI’s VP of Hardware, shares early results from Jalapeño, OpenAI’s first custom inference chip. He explains how it is already proven to make ChatGPT responses faster and Codex sessions and agents more responsive. He also discusses how OpenAI models helped the team design and improve the chip, and why developing the models, software, and infrastructure together was so important. Finally, Richard looks ahead to deploying Jalapeño across OpenAI’s compute infrastructure and building future generations of the chip.

This OpenAI Forum event explored how K–12 educators and school leaders are using AI to improve teaching, learning, and district operations. District leaders described a shift from experimenting with AI to redesigning workflows, strengthening professional capacity, and rapidly prototyping solutions to real problems. A fourth-grade teacher demonstrated a “pedagogy first, AI second” approach in which ChatGPT helps her create differentiated supports based on standards and student work while she retains instructional judgment. The discussion emphasized responsible adoption, including parent transparency, student privacy, human oversight, and ensuring that time saved ultimately leads to stronger teacher-student relationships and improved learning.

Amy Deng shared how she used ChatGPT and Codex while navigating fatigue after treatment for a benign brain tumor. She described complex care as an information-management challenge, with important details spread across appointments, records, and daily experiences. AI helped her collect and organize that information so she could arrive at appointments better prepared and give her clinicians more context. She also demonstrated a Codex skill that turns spoken symptom notes into structured records when typing feels difficult. Her broader point was that AI can help patients participate more actively in their care while leaving medical decisions to clinicians. If you’d like to learn more about Amy’s work, visit amydeng.me.

OpenAI’s Chris Lehane and Morgan Dwyer sit down with the company’s head of finance communications, Josh King, for a brisk tour of the company’s latest updates. Lehane casts OpenAI’s momentum as a fast-turning flywheel: better models draw more users and grow more revenue. That, in turn, funds the compute needed for the next technological leap. Dwyer makes a compelling case, drawn from our paper, “Industrial Policy for the Intelligence Age,” that the road to superintelligence should be democratic, worker-centered and broadly beneficial, with outside researchers pressure-testing big ideas on economic security and frontier safety. Finally, Lehane fills us in on the new ChatGPT for teens and why it’s a safer, more thoughtful tool for learning.